Video
Video
(IBD)?
testTiago Capitão2024-08-14T11:37:56+00:00
What is Inflammatory Bowel Disease
(IBD)?
Inflammatory bowel disease (IBD) is a chronic disorder characterized by inflammation of the digestive tract. It includes conditions like Crohn's disease (CD) and ulcerative colitis (UC).
What are Glycans?
Glycans, also called polysaccharides, are sugar chains that serve several functions in our bodies (structural, energy storage, and regulatory functions). The array of glycans in our gut (the glycome) plays an important role in the correct function and protection of our gut and its balanced interaction with microorganisms.
What is the GlycanTrigger project?
GlycanTrigger is a project funded by the European Union that looks into how changes in glycans (the sugar chains) on the surface of the gut mucosa can act as a trigger of health to chronic inflammation transition
Why is GlycanTrigger’s approach different?
GlycanTrigger is testing the innovative hypothesis that changes in glycans composition of the protective layer of our gut (the glycocalyx) act as an early event of the inflammatory response. This glycan switch at the surface of gut mucosa can lead to an imbalance in the bacteria living in our gut (i.e., the gut microbiome), triggering the inflammatory response.
(IBD)?
